A calorie-restricted diet mimicking the effects of fasting may reverse the symptoms of multiple sclerosis and help mend the damage caused by the disorder.
Scientists are so excited regarding the finding that they are moving to individual trials that are big and are advocating it for quite ill patients ‘who cannot wait.’
The regime just entails cutting calorie counts that are standard in half for three days in every seven.
It’s thought the immune system attacks the protective coating on nerve cells in the mind and spinal cord, leading to inflammation and pain, impairment and death, in severe cases, even though it is uncertain what causes MS.
I really believe MS patients who cannot wait can try this now, says Valter Longo.
Human MS patients who were set on the diet to check that it was not dangerous to their health, also reported enriched quality of life and scored better on the Extended Disability Status Scale (EDSS) which evaluates movement, tremors, language, and swallowing.
“Since the pilot human trial was small, now we are setting up a big multi-centre clinical trial. But because we’ve already analyzed this and similar diets with various disorders on hundreds of patients, I consider this may be attempted now by MS patients who cannot wait.”
An MRI scan revealing multiple sclerosis discovered the diet trips a passing-and-life process for cells that appears essential for the body’s repair.
These latest findings follow studies by precisely the same USC lab the diet, can completely reboot the immune system
In a different study published last year, the Longo group found that visceral belly fat can be reduced by the diet and reduce markers of aging.
“We began thinking: If it turns on the stem cells and kills lots of immune cells, is it feasible that maybe the bad ones will be killed by it and after that generate new ones that were good?” added Prof Longo said. “ That’s why we started this study.”
“During the fasting-mimicking diet, cortisone is created and that starts a killing of autoimmune cells. This process also results in the creation of new healthy cells.”
Results demonstrated the fasting-mimicking diet reduced disease symptoms in all of the mice and healed 20 percent totally.
In addition, they found a decrease in the inflammation-causing cytokines – proteins that purchase other cells to mend sites of trauma, illness or other pain.
And they found that white blood T cells, responsible for resistance, were boosted.
Finally, the researchers found the fasting-mimicking diet encourages regeneration of the myelin – the sheath of fats and proteins that insulate nerve fibers in the spine and brain – that’s damaged by the autoimmunity.
Nick Rijke, Executive Director of Policy and Research in the MS Society said: “Diet is an one that we understand many people with MS are interested in and an emerging area of MS research. While this study demonstrated encouraging results into the consequence of fasting on animal models on MS, there was not a lot of investigation into the benefits for individuals with MS, and that’s why we’re funding research within this area.”